Quality
Verified purity. Documented every step.
We don't ask you to trust us — we show you. Every batch comes with a third-party Certificate of Analysis, cold-chain shipping when it matters, and a paper trail you can audit.
Third-party tested
Every batch verified by independent labs for purity, identity, and endotoxins. COA available before you buy.
Cold-chain shipping
Temperature-controlled packaging for sensitive compounds. Fast US fulfillment with tracked delivery.
Transparent sourcing
USA-synthesized peptides with documented provenance — no mystery vials, no rebrands.
What is a COA?
Certificate of Analysis, explained.
A Certificate of Analysis (COA) is the lab-issued document that proves what's in the vial. It's produced by an independent, third-party analytical laboratory — not by us — after they physically test material pulled from the same batch you receive.
Each COA ties a specific batch number to a set of measured results, so you can verify the compound is what the label says it is, at the purity the label claims, free of contaminants that would compromise research use.
Every COA we issue includes:
- Identity. LC-MS confirms the molecular mass matches the reference standard.
- Purity. RP-HPLC quantifies the target peptide (we target ≥ 99%).
- Water & acetate content. Karl Fischer + ion chromatography for accurate net-peptide weight.
- Endotoxins. LAL assay — critical for any injectable research application.
- Bioburden & heavy metals. Microbial and elemental contamination screening.
- Batch traceability. Lot #, manufacture date, test date, expiry, and storage conditions.
View COAs online
See exactly what you get with every batch.
Every Certificate of Analysis is available on our website — no PDFs, ZIPs, or downloads. Review purity, CAS number, molecular formula, methods, specifications, and the full analytical results table for every product we ship, right in your browser.
Shareable link · Nothing to download
Reading a COA
What's on every COA — and how to read the results.
A COA looks technical, but it's really just three questions with numbers attached: is it the right molecule, how pure is it, and is it clean enough to use. Here's what each test measures, the specification we hold every batch to, and what a result actually means when you're deciding whether to accept a vial into your workflow.
Identity
Mass Spectrometry (LC-MS)
Spec: Observed [M+H]⁺ matches theoretical mass ± 0.5 Da
How to read it: Confirms the peptide in the vial is the exact molecule on the label. A matching mass = correct sequence. A mismatch — even close — means a different (or misfolded) compound; reject the batch.
Sequence Confirmation (MS/MS, when applicable)
Spec: Fragment ions map to expected amino-acid sequence
How to read it: Extra assurance for longer peptides. Confirms not just the mass but the order of residues.
Purity
Reverse-Phase HPLC (RP-HPLC, UV 220 nm)
Spec: ≥ 98.0 % (we target ≥ 99 %)
How to read it: The single most important number on the COA. It's the percentage of the sample that IS the target peptide. Everything else is truncated sequences, side products, or salts. Divide your dose math by this figure for accurate net-peptide weight.
Water Content (Karl Fischer)
Spec: ≤ 8.0 %
How to read it: Lyophilized peptides always contain some residual water. Higher water = less peptide per mg. If you're weighing out material, subtract this to get true net weight.
Counter-Ion / Acetate Content (Ion Chromatography)
Spec: ≤ 12.0 % (typical for TFA-free acetate salts)
How to read it: Peptides ship as salts. This is the % of the powder that's counter-ion, not peptide. Combine with water content to calculate true peptide mass in each vial.
Contaminants & Safety
Endotoxins (LAL — Kinetic Chromogenic)
Spec: < 5 EU/mg (we typically report < 0.5 EU/mg)
How to read it: Endotoxins are bacterial cell-wall fragments that trigger inflammatory responses in cell culture and animal models. Critical for any injectable research application. Lower is always better; a pass here means the peptide won't confound your immunology or in-vivo data.
Bioburden (USP <61>)
Spec: < 100 CFU/g total aerobic count
How to read it: Total live microbial count. Confirms the batch wasn't contaminated during synthesis or lyophilization.
Heavy Metals (ICP-MS)
Spec: ≤ 10 ppm (typically < 1 ppm)
How to read it: Screens for lead, arsenic, cadmium, and mercury carried over from synthesis reagents. Elevated heavy metals can skew enzyme assays and cell-viability results.
Residual Solvents (GC-MS)
Spec: USP <467> compliant
How to read it: Confirms manufacturing solvents (acetonitrile, DMF, TFA, etc.) have been evaporated below toxicity thresholds.
Batch Traceability
Header Block
Spec: Product name, CAS #, molecular formula & weight, lot #, manufacture date, test date, expiry, storage conditions
How to read it: Every result on the COA is tied to a specific lot number that also appears on your vial label. If the lot on your COA doesn't match the lot on your vial, it's the wrong document — request the right one.
Conclusion & QA Signature
Spec: Signed release by QC Analyst and reviewed by QA Manager
How to read it: A signed release means the batch met every specification above and was authorized for distribution. Unsigned or 'preliminary' COAs are not release documents.
Quick reference: what "PASS" means
Every row on the COA has a Specification (the maximum or minimum acceptable value) and a Result (what the lab actually measured). If the result is inside the specification, the row is marked PASS. A batch is only released when every row passes. If you see any FAIL, WARN, or "not tested" entry on a release COA, contact us before using the material.